Article
Combined cadmium and thiuram show synergistic toxicity and induce mitochondrial petite mutants.
Environmental science & technology - 15 Nov 2007
Iwahashi Hitoshi, Ishidou Emi, Kitagawa Emiko, Momose Yuko
Abstract excerpt
A bioassay is a system for monitoring toxicity of chemicals in the environment via the biological responses of experimental organisms. These responses can be detected by analysis of genome-wide changes in mRNA expression levels using DNA microarrays. We applied this system for evaluation of synergistic toxicity by cadmium and thiuram, as this combination showed mutual growth inhibition in yeast. Hierarchical...
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