Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toxicogenomics and systems toxicology: aims and prospects.

Nature reviews. Genetics - 1 Dec 2004

Waters Michael D, Fostel Jennifer M

Abstract excerpt

Toxicogenomics combines transcript, protein and metabolite profiling with conventional toxicology to investigate the interaction between genes and environmental stress in disease causation. The patterns of altered molecular expression that are caused by specific exposures or disease outcomes have revealed how several toxicants act and cause disease. Despite these success stories, the field faces noteworthy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to Databases, Factual
Share to Ecology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Forecasting

Share to Gene Expression Profiling

Share to Proteomics

Share to Toxicogenetics

Share to Toxicology

Source

Identifiers

PMID: 15573125
DOI: 10.1038/nrg1493

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toxicogenomics and systems toxicology: aims and prospects.PMID 15573125Read ↗

An overview of toxicogenomics.Semantic proximity Read ↗

Toxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies.Semantic proximity Read ↗

Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base.Semantic proximity Read ↗

Toxicogenomics and clinical toxicology: an example of the connection between basic and applied sciences.Semantic proximity Read ↗

Toxicoproteomics and its application to human health risk assessment.Semantic proximity Read ↗

Unbiased Approach for the Identification of Molecular Mechanisms Sensitive to Chemical ExposuresSemantic proximity Read ↗

Moving beyond a descriptive aquatic toxicology: the value of biological process and trait information.Semantic proximity Read ↗

Use of traditional end points and gene dysregulation to understand mechanisms of toxicity: toxicogenomics in mechanistic toxicology.Semantic proximity Read ↗

Systems biology approaches to evaluate arsenic toxicity and carcinogenicity: an overview.Semantic proximity Read ↗

Knowledge-Driven Approaches to Create the MTox700+ Metabolite Panel for Predicting Toxicity.Semantic proximity Read ↗

Toxicogenomics and studies of genomic effects of dietary components.Semantic proximity Read ↗

Underexplored Molecular Mechanisms of ToxicitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.