Toxicogenomics and systems toxicology: aims and prospects.

doi:10.1038/nrg1493

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Article

Toxicogenomics and systems toxicology: aims and prospects.

Nature reviews. Genetics - 1 Dec 2004

Waters Michael D, Fostel Jennifer M

Abstract excerpt

Toxicogenomics combines transcript, protein and metabolite profiling with conventional toxicology to investigate the interaction between genes and environmental stress in disease causation. The patterns of altered molecular expression that are caused by specific exposures or disease outcomes have revealed how several toxicants act and cause disease. Despite these success stories, the field faces noteworthy...

Topics

Animals
Computational Biology
Databases, Factual
Ecology
Forecasting
Gene Expression Profiling
Genetic Predisposition to Disease
Humans
Proteomics
Systems Theory
Toxicogenetics
Toxicology

Source

Open in PubMed

Identifiers

PMID: 15573125
DOI: 10.1038/nrg1493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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