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Article

Association of methylenetetrahydrofolate reductase genetic polymorphisms with atlantoaxial dislocation.

Journal of neurosurgery. Spine - 1 Dec 2007

Pradhan Mandakini, Behari Sanjay, Kalra Samir K, Ojha Priti, Agarwal Sarita, Jain Vijendra K

Abstract excerpt

OBJECT: Genetic mechanisms of atlantoaxial dislocation (AAD) have not previously been elucidated. The authors studied association of polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, which encodes enzymes of the folate pathway (implicated in causation of neural tube defects [NTDs]), in patients with AAD. METHODS: Molecular analysis of MTHFR polymorphisms (677C-->T, cytosine to thymine and,...

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Source

Identifiers

PMID: 18074687
DOI: 10.3171/SPI-07/12/623

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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