Article
Xenogenic transfer of isolated murine mitochondria into human rho0 cells can improve respiratory function.
Rejuvenation research - 1 Dec 2007
Katrangi Eyad, D'Souza Gerard, Boddapati Sarathi V, Kulawiec Mariola, Singh Keshav K, Bigger Brian, Weissig Volkmar
Abstract excerpt
Mitochondrial DNA mutations are the direct cause of several physiological disorders and are also associated with the aging process. The modest progress made over the past two decades towards manipulating the mitochondrial genome and understanding its function within living mammalian cells means that cures for mitochondrial DNA mutations are still elusive. Here, we report that transformed mammalian cells...
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