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Article

A single mutation in chikungunya virus affects vector specificity and epidemic potential.

PLoS pathogens - 1 Dec 2007

Tsetsarkin Konstantin A, Vanlandingham Dana L, McGee Charles E, Higgs Stephen

Abstract excerpt

Chikungunya virus (CHIKV) is an emerging arbovirus associated with several recent large-scale epidemics. The 2005-2006 epidemic on Reunion island that resulted in approximately 266,000 human cases was associated with a strain of CHIKV with a mutation in the envelope protein gene (E1-A226V). To test the hypothesis that this mutation in the epidemic CHIKV (strain LR2006 OPY1) might influence fitness for different...

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Identifiers

PMID: 18069894
DOI: 10.1371/journal.ppat.0030201
PMCID: PMC2134949

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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