Article
Importance of mosquito "quasispecies" in selecting an epidemic arthropod-borne virus.
Scientific reports - 7 Jul 2016
Vazeille Marie, Zouache Karima, Vega-Rúa Anubis, Thiberge Jean-Michel, Caro Valérie, Yébakima André, Mousson Laurence, Piorkowski Géraldine, Dauga Catherine, Vaney Marie-Christine, Manni Mosè, Gasperi Giuliano, de Lamballerie Xavier, Failloux Anna-Bella
Abstract excerpt
Most arthropod-borne viruses (arboviruses), perpetuated by alternation between a vertebrate host and an insect vector, are likely to emerge through minor genetic changes enabling the virus to adapt to new hosts. In the past decade, chikungunya virus (CHIKV; Alphavirus, Togaviridae) has emerged on La Réunion Island following the selection of a unique substitution in the CHIKV E1 envelope glycoprotein (E1-A226V) of...
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