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Article

The 677 C/T MTHFR polymorphism is associated with essential hypertension, coronary artery disease, and higher homocysteine levels.

Archives of medical research - 1 Jan 2008

Ilhan Nevin, Kucuksu Mehmet, Kaman Dilara, Ilhan Necip, Ozbay Yilmaz

Abstract excerpt

BACKGROUND: Essential hypertension (EH) and cardiovascular disease are common, multifactorial disorders likely to be influenced by multiple genes of modest effect. The C677T methylenetetrahydrofolate reductase (MTHFR) gene polymorphism is related to MTHFR enzyme activity and to plasma homocysteine (Hcy) concentration. This study was designed to investigate an association of this polymorphism with coronary artery...

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Source

Identifiers

PMID: 18068006
DOI: 10.1016/j.arcmed.2007.07.009

Genes

CAD
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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The 677 C/T MTHFR polymorphism is associated with essential hypertension, coronary artery disease, and higher homocysteine levels.PMID 18068006Read ↗

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