Article
Characterization of the ETnII-alpha endogenous retroviral element in the BALB/cJ Zhx2 ( Afr1 ) allele.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2008
Perincheri Sudhir, Peyton David K, Glenn Michelle, Peterson Martha L, Spear Brett T
Abstract excerpt
Integration of mouse endogenous retroviral (MERV) elements is responsible for an estimated 10% of spontaneous mutations that have been characterized in the laboratory mouse. We recently identified a MERV integration in the first intron of the Zinc fingers and homeoboxes 2 (Zhx2) gene in BALB/cJ mice, resulting in reduced Zhx2 expression. This integration is found in BALB/cJ but not in other BALB/c substrains,...
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