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Article

Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene.

The EMBO journal - 1 May 1990

Ashworth A, Skene B, Swift S, Lovell-Badge R

Abstract excerpt

ZFY, a gene on the Y chromosome encoding a zinc finger protein, has been proposed as a candidate for the human testis determining gene. Sequences related to ZFY, called ZFX, are present on the X chromosome of a wide range of placental mammals. Unlike most mammals the mouse has four genes homologous to ZFY; two on the Y chromosome, Zfy-1 and Zfy-2, an X-linked gene, Zfx, and an autosomal gene, Zfa. We show here...

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Source

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Identifiers

PMID: 1691708
DOI: 10.1002/j.1460-2075.1990.tb08271.x
PMCID: PMC551846

Genes

ZFY
ZFX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene.PMID 1691708Read ↗

Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus.Semantic proximity Read ↗

Characterisation of the non-canonical zinc finger protein ZFP263 in mouseSemantic proximity Read ↗

Novel gene conversion between X-Y homologues located in the nonrecombining region of the Y chromosome in Felidae (Mammalia).Semantic proximity Read ↗

The Mouse Y Chromosome Interval Necessary for Spermatogonial Proliferation is Gene Dense with Syntenic Homology to the Human AZFa RegionSemantic proximity Read ↗

Evolution of the X-linked zinc finger gene and the Y-linked zinc finger gene in primates.Semantic proximity Read ↗

Adaptive evolution in zinc finger transcription factors.Semantic proximity Read ↗

Zfy gene expression patterns are not compatible with a primary role in mouse sex determination.Semantic proximity Read ↗

A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonadsSemantic proximity Read ↗

Characterization of the ETnII-alpha endogenous retroviral element in the BALB/cJ Zhx2 ( Afr1 ) allele.Semantic proximity Read ↗

Estimating the intensity of male-driven evolution in rodents by using X-linked and Y-linked Ube 1 genes and pseudogenes.Semantic proximity Read ↗

ZFY gene expression and retention in human prostate adenocarcinomaSemantic proximity Read ↗

Mouse and zebrafish Hoxa3 orthologues have nonequivalent in vivo protein function.Semantic proximity Read ↗

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