Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pheochromocytoma penetrance varies by RET mutation in MEN 2A.

Surgery - 1 Dec 2007

Quayle Frank J, Fialkowski Elizabeth A, Benveniste Ronald, Moley Jeffrey F

Abstract excerpt

BACKGROUND: The occurrence of pheochromocytoma in multiple endocrine neoplasia type 2A (MEN 2A) carriers varies greatly. This study aims to determine PC expression for specific MEN 2A RET mutations. METHODS: Charts of MEN 2A patients enrolled in our multiple endocrine neoplasia program from 1990 to 2001 were reviewed retrospectively. Statistical analysis was performed using SAS software (SAS Institute, Inc, Cary,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Gland Neoplasms
Share to Amino Acid Substitution
Share to Codon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Multiple Endocrine Neoplasia Type 2a

Share to Penetrance

Share to Pheochromocytoma

Share to Proto-Oncogene Proteins c-ret

Source

Identifiers

PMID: 18063059
DOI: 10.1016/j.surg.2007.09.013

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pheochromocytoma penetrance varies by RET mutation in MEN 2A.PMID 18063059Read ↗

High penetrance of pheochromocytoma in multiple endocrine neoplasia 2 caused by germ line RET codon 634 mutation in Japanese patients.Semantic proximity Read ↗

Phaeochromocytoma in multiple endocrine neoplasia type 2: RET codon‐specific penetrance and changes in management during the last four decadesSemantic proximity Read ↗

The Relationship Between Specific RET Proto-oncogene Mutations and Disease Phenotype in Multiple Endocrine Neoplasia Type 2Semantic proximity Read ↗

Molecular implications of RET mutations for pheochromocytoma risk in multiple endocrine neoplasia 2.Semantic proximity Read ↗

The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis.Semantic proximity Read ↗

Multiple endocrine neoplasia type 2: evaluation of the genotype-phenotype relationship.Semantic proximity Read ↗

The characterization of pheochromocytoma and its impact on overall survival in multiple endocrine neoplasia type 2.Semantic proximity Read ↗

Codon-specific development of pheochromocytoma in multiple endocrine neoplasia type 2.Semantic proximity Read ↗

Distribution of RET Mutations in Multiple Endocrine Neoplasia 2 in Denmark 1994–2014: A Nationwide StudySemantic proximity Read ↗

RET proto-oncogene mutations are restricted to codons 634 and 918 in mainland Chinese families with MEN2A and MEN2B.Semantic proximity Read ↗

The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A.Semantic proximity Read ↗

RET Cys634Arg mutation confers a more aggressive multiple endocrine neoplasia type 2A phenotype than Cys634Tyr mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.