Article
Biomarkers in clear cell renal cell carcinoma.
Expert review of anticancer therapy - 1 Dec 2007
George Saby, Bukowski Ronald M
Abstract excerpt
The treatment of advanced renal cell carcinoma (RCC) has evolved significantly following the identification of the von Hippel-Lindau (VHL) gene and the function of its protein, and subsequent development of antiangiogenic therapies. A series of clinical trials resulted in the approval of three new agents with significant activity in this disease. Additional studies are now underway to identify subsets of patients...
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