Article
Molecular biomarkers in advanced renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2014
Maroto Pablo, Rini Brian
Abstract excerpt
The availability of agents directly targeting tumorigenic and angiogenic pathways has significantly improved the outcomes of patients with advanced renal cell carcinoma (RCC) in recent years. However, all patients eventually become resistant and a substantial percentage experience immediate disease progression with first-line targeted therapy. In addition, patients have variable clinical benefit and/or tolerance...
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