Article
Latent autoimmune diabetes in adults differs genetically from classical type 1 diabetes diagnosed after the age of 35 years.
Diabetes care - 1 Sept 2010
Andersen Mette K, Lundgren Virve, Turunen Joni A, Forsblom Carol, Isomaa Bo, Groop Per-Henrik, Groop Leif, Tuomi Tiinamaija
Abstract excerpt
OBJECTIVE: We studied differences between patients with latent autoimmune diabetes in adults (LADA), type 2 diabetes, and classical type 1 diabetes diagnosed after age 35 years. RESEARCH DESIGN AND METHODS: Polymorphisms in HLA-DQB1, INS, PTPN22, and CTLA4 were genotyped in patients with LADA (n = 213), type 1 diabetes diagnosed at >35 years of age (T1D(>35y); n = 257) or <20 years of age (T1D(<20y); n = 158),...
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