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Latency and Persistence of Respiratory Syncytial Virus Despite T Cell Immunity

26 Jan 2004

Abstract excerpt

Respiratory syncytial virus (RSV) causes bronchiolitis in infants, which is associated with recurrent wheezing in later childhood. There is mounting evidence that the virus becomes latent or persists in vivo, but little is known about the mechanisms of its latency, persistence, and immune evasion. We therefore infected BALB/c mice intranasally with human RSV, analyzed sequential tissue samples by direct culture...

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PMID: 14742302
DOI: 10.1164/rccm.200308-1203oc

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