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Article

Tiling of r7 axons in the Drosophila visual system is mediated both by transduction of an activin signal to the nucleus and by mutual repulsion.

Neuron - 6 Dec 2007

Ting Chun-Yuan, Herman Tory, Yonekura Shinichi, Gao Shuying, Wang Jian, Serpe Mihaela, O'Connor Michael B, Zipursky S Lawrence, Lee Chi-Hon

Abstract excerpt

The organization of neuronal wiring into layers and columns is a common feature of both vertebrate and invertebrate brains. In the Drosophila visual system, each R7 photoreceptor axon projects within a single column to a specific layer of the optic lobe. We refer to the restriction of terminals to single columns as tiling. In a genetic screen based on an R7-dependent behavior, we identified the Activin receptor...

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Identifiers

PMID: 18054857
DOI: 10.1016/j.neuron.2007.09.033
PMCID: PMC2693211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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