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Article

Association of autism with polymorphisms in the paired-like homeodomain transcription factor 1 (PITX1) on chromosome 5q31: a candidate gene analysis.

BMC medical genetics - 6 Dec 2007

Philippi Anne, Tores Frédéric, Carayol Jérome, Rousseau Francis, Letexier Mélanie, Roschmann Elke, Lindenbaum Pierre, Benajjou Abdel, Fontaine Karine, Vazart Céline, Gesnouin Philippe, Brooks Peter, Hager Jörg

Abstract excerpt

BACKGROUND: Autism is a complex, heterogeneous, behaviorally-defined disorder characterized by disruptions of the nervous system and of other systems such as the pituitary-hypothalamic axis. In a previous genome wide screen, we reported linkage of autism with a 1.2 Megabase interval on chromosome 5q31. For the current study, we hypothesized that 3 of the genes in this region could be involved in the development...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18053270
DOI: 10.1186/1471-2350-8-74
PMCID: PMC2222245

Genes

PITX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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