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Article

A novel splicing variant of proprotein convertase subtilisin/kexin type 9.

DNA and cell biology - 1 Apr 2008

Schmidt Robert J, Zhang Youyan, Zhao Yang, Qian Yue-Wei, Wang He, Lin Aimin, Ehsani Maria E, Yu Xiaohong, Wang Guoming, Singh Jaipal, Su Eric W, Li Shuyu, Konrad Robert J, Cao Guoqing

Abstract excerpt

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is the most recently identified member of the proprotein convertase family. Genetic and cell biology studies have suggested a critical role of PCSK9 in regulating low-density lipoprotein receptor (LDLR) protein levels and thus modulating plasma LDL cholesterol. Recent data on the molecular basis for PCSK9 action support the model in which PCSK9 is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18052825
DOI: 10.1089/dna.2007.0667

Genes

PCSK9
LDLR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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