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Article

Lentiviral Vector Gene Transfer to Porcine Airways

1 Jan 2012

Abstract excerpt

In this study, we investigated lentiviral vector development and transduction efficiencies in well-differentiated primary cultures of pig airway epithelia (PAE) and wild-type pigs in vivo. We noted gene transfer efficiencies similar to that observed for human airway epithelia (HAE). Interestingly, feline immunodeficiency virus (FIV)-based vectors transduced immortalized pig cells as well as pig primary cells more...

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PMID: 23187455
DOI: 10.1038/mtna.2012.47

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