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Article

Mutation analysis of candidate genes SCN1B, KCND3 and ANK2 in patients with clinical diagnosis of long QT syndrome.

Physiological research - 1 Jan 2008

Raudenská M, Bittnerová A, Novotný T, Floriánová A, Chroust K, Gaillyová R, Semrád B, Kadlecová J, Šišáková M, Toman O, Spinar J

Abstract excerpt

The long QT syndrome (LQTS) is a monogenic disorder characterized by prolongation of the QT interval on electrocardiogram and syncope or sudden death caused by polymorphic ventricular tachycardia (torsades de pointes). In general, mutations in cardiac ion channel genes (KCNQ1, KCNH2, SCN5A, KCNE1, KCNE2) have been identified as a cause for LQTS. About 50-60 % of LQTS patients have an identifiable LQTS causing...

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Source

Identifiers

PMID: 18052691
DOI: 10.33549/physiolres.931184

Genes

KCND3
ANK2
KCNH2
KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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