Article
[Molecular epidemiology of pneumococci with decreased susceptibility to penicillin isolated in a Parisian pediatric hospital].
Pathologie-biologie - 1 May 1996
Moissenet D, Guet L, Valcin M, Garabedian E N, Geslin P, Garbarg-Chenon A, Vu-Thien H
Abstract excerpt
Pneumococci with decreased susceptibility or resistant to penicillin (PRP) have been isolated with an increasing frequency in France. Among PRP, isolates of serotypes 23F and 9V were the most frequently recovered in our children's hospital. Penicillin-resistance is due to the appearance of altered penicillin binding proteins (PBPs) with reduced affinity for beta-lactam antibiotics. 3 PBPs have been well studied,...
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