Article
Prospects for prevention of otitis media.
The Pediatric infectious disease journal - 1 Oct 2007
Pelton Stephen I
Abstract excerpt
Understanding the pathogenesis of acute otitis media provides insight into strategies for immunoprophylaxis. This article evaluates the interactions between pathogen and host defense, and identifies potential bacterial and viral vaccine targets. Discussed in detail are the attributes for a candidate antigen necessary to achieve a greater reduction in the burden of middle ear disease. These include: (1) the need...
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