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Article

Coculture of Spermatogonia With Somatic Cells in a Novel Three‐Dimensional Soft‐Agar‐Culture‐System

18 Apr 2008

Abstract excerpt

Isolation and culture of spermatogonial stem cells (SSCs) has become an approach to study the milieu and the factors controlling their expansion and differentiation. Traditional conventional cell culture does not mimic the complex situation in the seminiferous epithelium providing a basal, intraepithelial, and adluminal compartment to the developing male germ cells. SSCs are located in specific stem cell niches...

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PMID: 18046051
DOI: 10.2164/jandrol.107.002857

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