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<i>In vitro</i>culture of testicular germ cells: Regulatory factors and limitations

1 Jan 2007

Abstract excerpt

Spermatogenesis is regulated mainly by endocrine factors and also by testicular paracrine/autocrine growth factors. These factors are produced by Sertoli cells, germ cells, peritubular cells and interstitial cells, mainly Leydig cells and macrophages. The interactions and the ratio between Sertoli and germ cells in the seminiferous tubules ensure successful spermatogenesis. In order to culture spermatogonial stem...

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PMID: 18092232
DOI: 10.1080/08977190701783400

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