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Concise Review: Spermatogenesis in an Artificial Three-Dimensional System

19 Sept 2012

Abstract excerpt

Culture of spermatogonial stem cells has been performed under a variety of conditions. Most featured two-dimensional systems, with different types of sera, conditioned media, feeder layers, and growth factors. Some have used three-dimensional (3D) matrices produced from gelatin, collagen, or other material. In spite of their increasingly sophisticated composition, however, complete spermatogenesis in vitro has...

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PMID: 22997006
DOI: 10.1002/stem.1238

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