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Article

Hsp40s specify functions of Hsp104 and Hsp90 protein chaperone machines.

PLoS genetics - 1 Oct 2014

Reidy Michael, Sharma Ruchika, Shastry Shankar, Roberts Brittany-Lee, Albino-Flores Ivan, Wickner Sue, Masison Daniel C

Abstract excerpt

Hsp100 family chaperones of microorganisms and plants cooperate with the Hsp70/Hsp40/NEF system to resolubilize and reactivate stress-denatured proteins. In yeast this machinery also promotes propagation of prions by fragmenting prion polymers. We previously showed the bacterial Hsp100 machinery...

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Source

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Identifiers

PMID: 25329162
DOI: 10.1371/journal.pgen.1004720
PMCID: PMC4199505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-25329162-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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