Article
Cholesteryl ester transfer protein polymorphism D442G associated with a potential decreased risk for Alzheimer's disease as a modifier for APOE epsilon4 in Chinese.
Brain research - 2 Jan 2008
Chen Da-Wei, Yang Jing-Fang, Tang Zhe, Dong Xiu-Min, Feng Xiu-Li, Yu Shun, Chan Piu
Abstract excerpt
There is compelling evidence indicating that reduction of high-density lipoprotein (HDL) level is associated with increased risk of Alzheimer's disease (AD). It is known that the levels of HDL are regulated by cholesteryl ester transfer protein (CETP) and several single nucleotide polymorphisms (SNPs) in the CETP gene have been shown to be associated with the levels of HDL. Therefore, it is assumed that the CETP...
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