Article
Changes in serum hepatitis B e antigen (HBeAg) levels associated with the emergence of YMDD mutants in HBeAg non-seroconverted patients during lamivudine therapy.
Liver international : official journal of the International Association for the Study of the Liver - 1 Dec 2007
Yen Yi-Hao, Lu Sheng-Nan, Chen Chien-Hung, Wang Jing-Houng, Wu Chun-Mei, Hung Chao-Hung, Tseng Po-Lin, Hu Tsung-Hui, Changchien Chi-Sin, Lee Chuan-Mo
Abstract excerpt
BACKGROUND: To elucidate the associations between the changing patterns of hepatitis B e antigen (HBeAg) levels and the emergence of tyrosine-methionine-aspartate-aspartate (YMDD) mutants in HBeAg non-seroconverted patients undergoing lamivudine therapy. METHODS: This study analysed 76 HBeAg-positive naïve chronic hepatitis B patients treated with lamivudine. The median duration of therapy was 52 weeks. The YMDD...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.