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Article

Rescue of oogenesis in Cx37-null mutant mice by oocyte-specific replacement with Cx43.

Journal of cell science - 1 Dec 2007

Li Tony Y, Colley Deanne, Barr Kevin J, Yee Siu-Pok, Kidder Gerald M

Abstract excerpt

Mammalian oocytes and surrounding granulosa cells are metabolically coupled via gap junctions. In growing follicles of the mouse, gap junctions between oocytes and granulosa cells are assembled from connexin 37 (Cx37, encoded by Gja4), whereas those between granulosa cells are assembled from connexin 43 (Cx43, encoded by Gja1). This spatial separation, and the different permeability properties of gap junctions...

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Identifiers

PMID: 18032785
DOI: 10.1242/jcs.03488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rescue of oogenesis in Cx37-null mutant mice by oocyte-specific replacement with Cx43.PMID 18032785Read ↗

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Oocyte–Granulosa Cell Heterologous Gap Junctions Are Required for the Coordination of Nuclear and Cytoplasmic Meiotic CompetenceSemantic proximity Read ↗

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Cx40.8, a Cx43-like protein, forms gap junction channels inefficiently and may require Cx43 for its association at the plasma membrane.Semantic proximity Read ↗

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