Article
Mapping quantitative trait loci for canine hip dysplasia in German Shepherd dogs.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2007
Marschall Yvonne, Distl Ottmar
Abstract excerpt
Canine hip dysplasia (CHD) is a common hereditary developmental disease of the coxofemoral joints. CHD is characterized by subluxation of the femoral head and deformation of the acetabulum leading to a painful osteoarthrosis. Analyses of mode of inheritance have shown the involvement of a major gene in expression of CHD in German Shepherd dogs. Thus, a whole genome scan for quantitative trait loci (QTL) was...
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