Article
An across-breed validation study of 46 genetic markers in canine hip dysplasia.
BMC genomics - 21 Jan 2021
Mikkola Lea, Kyöstilä Kaisa, Donner Jonas, Lappalainen Anu K, Hytönen Marjo K, Lohi Hannes, Iivanainen Antti
Abstract excerpt
BACKGROUND: Canine hip dysplasia (CHD) is a common disease, with a complex genetic background. Dogs with severe CHD sometimes also suffer from osteoarthritis (OA), an inflammatory, often painful and incurable condition. Previous studies have reported breed-specific genetic loci associated with different hip dysplasia and OA phenotypes. However, the independent replication of the known associations within or...
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