Article
Implication of the molecular characterization of acute myeloid leukemia.
Hematology. American Society of Hematology. Education Program - 1 Jan 2007
Döhner Hartmut
Abstract excerpt
The identification of molecular genetic alterations such as gene mutations or deregulated gene expression in acute myeloid leukemia (AML) has greatly advanced our understanding of leukemogenesis. These markers now allow us to unravel the enormous heterogeneity seen within cytogenetically defined subgroups of AML. Furthermore, the molecular alterations are providing targets for molecular therapies. In this...
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