Article
Calcitonin may be a useful therapeutic agent for osteoclastogenesis syndromes involving premature eruption of the tooth.
Medical hypotheses - 1 Jan 2008
Qin Han, Yang Fu Sheng
Abstract excerpt
Tooth eruption is a complex and tightly regulated process that involves cells of the tooth organ and the surrounding alveolus. Recent researches have shown that tooth eruption depends on the presence of osteoclasts to create an eruption pathway through the alveolar bone. The most important physiologic role likely being at the eruptive site, in the formation of osteoclasts through signaling via the RANKL/OPG...
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