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Article

Chronology and regulation of gene expression of RANKL in the rat dental follicle

1 Oct 2005

Abstract excerpt

Tooth eruption in the rat requires bone resorption resulting from a major burst of osteoclastogenesis on postnatal day 3 and a minor burst of osteoclastogenesis on postnatal day 10 in the alveolar bone of the first mandibular molar. The dental follicle regulates the major burst on postnatal day 3 by down-regulating its osteoprotegerin (OPG) gene expression to enable osteoclastogenesis to occur. To determine the...

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PMID: 16202028
DOI: 10.1111/j.1600-0722.2005.00245.x

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