Article
Maintenance and stabilization of mtDNA can be facilitated by the DNA-binding activity of Ilv5p.
Biochimica et biophysica acta - 1 Jan 2008
Macierzanka Malgorzata, Plotka Magdalena, Pryputniewicz-Drobinska Diana, Lewandowska Agnieszka, Lightowlers Robert, Marszalek Jaroslaw
Abstract excerpt
Mitochondrial DNA (mtDNA) is inherited as a protein-DNA complex (the nucleoid). Proteins associated with the nucleoid are not only components directly involved in maintenance and propagation of mtDNA but can also be bi-functional enzymes whose metabolic activities are not directly related to mtDNA stability. In the yeast Saccharomyces cerevisiae, one such enzyme, Ilv5p is required for branch chain amino acid...
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