Article
Transmission of drug-resistant HIV-1 from an infected individual to a caregiver.
Antiviral therapy - 1 Jan 2007
Brumme Chanson J, Harrigan P Richard, Preston Emma C, Dong Winnie W Y, Wynhoven Brian, Murphy Carol, Montaner Julio S G
Abstract excerpt
OBJECTIVE: To describe a suspected case of intrafamilial transmission of drug-resistant HIV-1 from an infected individual to his caregiver. METHODS: HIV-1 protease, reverse transcriptase, nef and gp41 DNA sequences were determined from plasma samples after RNA extraction and nested RT-PCR. Phylogenetic trees were generated using neighbour-joining methods. RESULTS: HIV-1 infection was diagnosed in an individual...
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