Article
Sexual development in Cryptococcus neoformans requires CLP1, a target of the homeodomain transcription factors Sxi1alpha and Sxi2a.
Eukaryotic cell - 1 Jan 2008
Ekena Joanne L, Stanton Brynne C, Schiebe-Owens Jessica A, Hull Christina M
Abstract excerpt
Sexual development in the human fungal pathogen Cryptococcus neoformans is a multistep process that results in the formation of spores, the likely infectious particles. A critical step in this developmental process is the transition from bud-form growth to filamentous growth. This transition is controlled by the homeodomain transcription factors Sxi1alpha and Sxi2a, whose targets are largely unknown. Here we...
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