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Genetic polymorphisms of XRCC1 gene and susceptibility to gastric cancer in Chinese Han population.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Sept 2013

Lu Zhengmao, Luo Tianhang, Nie Mingming, Bi Jianwei, Ke Chongwei, Xue Xuchao, Ma Liye, Fang Guoen

Abstract excerpt

This study aims to evaluate whether the c.1471G > A and c.1686C > G genetic polymorphisms of XRCC1 gene influencing gastric cancer susceptibility. A total of 813 subjects with Chinese Han ethnicity were enrolled. Our data suggest that the allele and genotype frequencies are significantly different from gastric cancer patients with cancer-free controls. We find that c.1471G > A and c.1686C > G genetic...

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Identifiers

PMID: 23919819
DOI: 10.3109/1354750X.2013.822562

Genes

XRCC1

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