Article
Interfering waves of adaptation promote spatial mixing.
Genetics - 1 Nov 2011
Martens Erik A, Hallatschek Oskar
Abstract excerpt
A fundamental problem of asexual adaptation is that beneficial substitutions are not efficiently accumulated in large populations: Beneficial mutations often go extinct because they compete with one another in going to fixation. It has been argued that such clonal interference may have led to the evolution of sex and recombination in well-mixed populations. Here, we study clonal interference, and mechanisms of...
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