Article
Detection of HPV subtypes by mass spectrometry in FFPE tissue specimens: a reliable tool for routine diagnostics.
Journal of clinical pathology - 1 May 2017
Kriegsmann Mark, Wandernoth Petra, Lisenko Katharina, Casadonte Rita, Longuespée Rémi, Arens Norbert, Kriegsmann Jörg
Abstract excerpt
AIMS: Human papilloma virus (HPV) infection is a causative agent for approximately 5% of all new cancer cases in humans. The virus is detected in cervical, anal, vaginal, penile, vulvar and head and neck cancers and has prognostic implications. Thus, test systems are required to detect high-risk but also low-risk HPV subtypes with high specificity and sensitivity in a time-effective and cost-effective manner. In...
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