Article
Myocardial 123metaiodobenzylguanidine uptake in genetic Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Jan 2008
Quattrone Aldo, Bagnato Antonio, Annesi Grazia, Novellino Fabiana, Morgante Letterio, Savettieri Giovanni, Zappia Mario, Tarantino Patrizia, Candiano Innocenza Claudia Cirò, Annesi Ferdinanda, Civitelli Donatella, Rocca Francesca Emanuela, D'Amelio Marco, Nicoletti Giuseppe, Morelli Maurizio, Petrone Alfredo, Loizzo Piercostanzo, Condino Francesca
Abstract excerpt
Myocardial (123)Metaiodobenzylguanidine (MIBG) enables the assessment of postganglionic sympathetic cardiac innervation. MIBG uptake is decreased in nearly all patients with Parkinson's disease (PD). Our objective was to evaluate MIBG uptake in patients with genetic PD. We investigated MIBG uptake in 14 patients with PD associated with mutations in different genes (Parkin, DJ-1, PINK1, and leucine-rich repeat...
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