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Article

Novel biochemical pathways of endoglin in vascular cell physiology

1 Nov 2007

Abstract excerpt

The broad role of the transforming growth factor beta (TGFbeta) signaling pathway in vascular development, homeostasis, and repair is well appreciated. Endoglin is emerging as a novel, complex, and poorly understood regulatory component of the TGFbeta receptor complex, whose importance is underscored by its recognition as the site of mutations causing hereditary hemorrhagic telangiectasia (HHT) [McAllister et...

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PMID: 17975795
DOI: 10.1002/jcb.21594

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