Article
An assessment of the Irish population for large-scale genetic mapping studies involving epilepsy and other complex diseases.
European journal of human genetics : EJHG - 1 Feb 2008
O'Dushlaine Colm T, Dolan Ciara, Weale Michael E, Stanton Alice, Croke David T, Kalviainen Reetta, Eriksson Kai, Kantanen Anne-Mari, Gibson Rachel A, Hosford David, Sisodiya Sanjay M, Gill Michael, Corvin Aiden P, Morris Derek W, Delanty Norman, Cavalleri Gianpiero L
Abstract excerpt
The recent completion of the International HapMap Project has rapidly advanced our understanding of linkage disequilibrium (LD) in the human genome. Today, tagging SNPs (tSNPs) can be quickly and easily selected and consequently HapMap data are regularly applied to both small- and large-scale genetic mapping studies. However, to correctly interpret the application of HapMap-derived tSNPs in a genetic mapping...
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