Article
Impact of Kir6.2 E23K polymorphism on the development of type 2 diabetes in a general Japanese population: The Hisayama Study.
Diabetes - 1 Nov 2007
Doi Yasufumi, Kubo Michiaki, Ninomiya Toshiharu, Yonemoto Koji, Iwase Masanori, Arima Hisatomi, Hata Jun, Tanizaki Yumihiro, Iida Mitsuo, Kiyohara Yutaka
Abstract excerpt
OBJECTIVE: The association between the E23K polymorphism of ATP-sensitive K(+) channel subunit Kir6.2 and diabetes has been reported in Caucasians but not in Asians. We examined this issue in follow-up and cross-sectional studies in a general Japanese population. RESEARCH DESIGN AND METHODS: In a 14-year follow-up study of 976 subjects aged 40-79 years with normal glucose tolerance (NGT), we investigated the...
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