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Article

Gene expression profiling to identify markers associated with deregulated hTERT in HPV‐transformed keratinocytes and cervical cancer

24 Oct 2007

Abstract excerpt

Although high-risk human papillomavirus (HPV) infection plays a major role in the development of cervical cancer, additive oncogenic events are involved as well. One key event involves increased activity of telomerase resulting from a deregulated expression of its catalytic subunit hTERT. Our previous microcell-mediated chromosome transfer studies revealed that introduction of human chromosome 6 in the...

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Share to Cervical Cancer and HPV Research
Share to Genomic variations and chromosomal abnormalities
Share to Telomeres, Telomerase, and Senescence

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PMID: 17960611
DOI: 10.1002/ijc.23210

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