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Article

Expression of <i>BORIS</i> in melanoma: Lack of association with <i>MAGE‐A1</i> activation

23 Oct 2007

Abstract excerpt

Several genes with specific expression in germ cells show aberrant activation in different types of tumors. These genes, termed cancer-germline (CG) genes, encode tumor-specific antigens, which represent potential targets for therapeutic vaccination against cancer. The germline-specific gene BORIS (Brother Of the Regulator of Imprinted Sites), which encodes an 11-zinc-fingers transcriptional regulator, was...

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PMID: 17957795
DOI: 10.1002/ijc.23140

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Expression of <i>BORIS</i> in melanoma: Lack of association with <i>MAGE‐A1</i> activationPMID 17957795Read ↗

Conditional Expression of the CTCF-Paralogous Transcriptional Factor BORIS in Normal Cells Results in Demethylation and Derepression of MAGE-A1 and Reactivation of Other Cancer-Testis GenesSemantic proximity Read ↗

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The Potential of BORIS Detected in the Leukocytes of Breast Cancer Patients as an Early Marker of TumorigenesisSemantic proximity Read ↗

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