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Article

The Potential of BORIS Detected in the Leukocytes of Breast Cancer Patients as an Early Marker of Tumorigenesis

15 Oct 2006

Abstract excerpt

PURPOSE: Brother of the regulator of imprinted sites (BORIS) is a novel member of the cancer-testis antigen gene family. These genes are normally expressed only in spermatocytes but abnormally activated in different malignancies, including breast cancer. The aim of this study was to investigate the expression of BORIS in the leukocytes of breast cancer patients and the correlation between BORIS levels and...

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PMID: 17062669
DOI: 10.1158/1078-0432.ccr-05-2731

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The Potential of BORIS Detected in the Leukocytes of Breast Cancer Patients as an Early Marker of TumorigenesisPMID 17062669Read ↗

BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumoursSemantic proximity Read ↗

Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression.Semantic proximity Read ↗

CTCFL/BORIS Is a Methylation-Independent DNA-Binding Protein That Preferentially Binds to the Paternal <i>H19</i> Differentially Methylated RegionSemantic proximity Read ↗

BORIS Binding to the Promoters of Cancer Testis Antigens, MAGEA2, MAGEA3, and MAGEA4, Is Associated with Their Transcriptional Activation in Lung CancerSemantic proximity Read ↗

Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factorsSemantic proximity Read ↗

Expression of <i>BORIS</i> in melanoma: Lack of association with <i>MAGE‐A1</i> activationSemantic proximity Read ↗

High Expression of hTERT and Stemness Genes in BORIS/CTCFL Positive Cells Isolated from Embryonic Cancer CellsSemantic proximity Read ↗

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