Article
Apolipoprotein A5-1131T>C polymorphism, but not APOE genotypes, increases susceptibility for dyslipidemia in children and adolescents.
Molecular biology reports - 1 Oct 2011
Brito D D V, Fernandes A P, Gomes K B, Coelho F F, Cruz N G, Sabino A P, Cardoso J E, Figueiredo-Filho P P, Diamante R, Norton C R, Sousa M O
Abstract excerpt
Apolipoprotein A5 (APOA5) and apolipoprotein E (APOE) play important roles in the metabolism of cholesterol and triglycerides. The aim of this study was to determine the allelic and genotypic distributions of the APOA5-1131T>C (rs 662799) and the APOE HhaI polymorphisms and to identify the association of both individual and combined APOA5-APOE genetic variants and the risk for dyslipidemia in children and...
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