Article
Contribution of the tdh1 gene of Kanagawa phenomenon-positive Vibrio parahaemolyticus to production of extracellular thermostable direct hemolysin.
Microbial pathogenesis - 1 Dec 1991
Nishibuchi M, Kumagai K, Kaper J B
Abstract excerpt
Kanagawa phenomenon-positive strains of Vibrio parahaemolyticus contain two copies of the tdh gene (tdh 1 and tdh 2) encoding thermostable direct hemolysin (TDH). Previous studies suggested that the tdh 2 gene, but not the tdh 1 gene, was responsible for production of extracellular TDH. In this study, a tdh 2-deficient isogenic mutant of Kanagawa phenomenon-positive strain AQ3815 was constructed by a suicide...
Topics
- Genes, Bacterial
- Hemolysin Proteins
- Mutation
- Vibrio parahaemolyticus