Article
Manifestation of the Kanagawa phenomenon, the virulence-associated phenotype, of Vibrio parahaemolyticus depends on a particular single base change in the promoter of the thermostable direct haemolysin gene.
Molecular microbiology - 1 Nov 1998
Okuda J, Nishibuchi M
Abstract excerpt
Thermostable direct haemolysin of Vibrio parahaemolyticus has been shown to be a major virulence factor. The Kanagawa phenomenon (KP), haemolysis induced by this haemolysin on a special blood agar medium, is strongly associated with clinical strains. We have been studying the expressions of vario...
Topics
- Bacterial Proteins
- Bacterial Toxins
- Base Sequence
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Hemolysin Proteins
- Lac Operon
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Phenotype
- Promoter Regions, Genetic
- Sequence Homology, Nucleic Acid
- Transcription, Genetic
- Vibrio parahaemolyticus
- Virulence
- beta-Galactosidase