Article
Enterotoxigenicity of Vibrio parahaemolyticus with and without genes encoding thermostable direct hemolysin.
Infection and immunity - 1 Sept 1992
Nishibuchi M, Fasano A, Russell R G, Kaper J B
Abstract excerpt
Vibrio parahaemolyticus produces a thermostable direct hemolysin (TDH) that has been implicated in the pathogenesis of diarrheal disease caused by this organism. However, previous studies attempting to demonstrate the contribution of the hemolysin to virulence have been inconclusive. We investigated this putative virulence factor by using an isogenic TDH-negative (TDH-) strain constructed by specifically...
Topics
- Animals
- Diarrhea
- Genes, Bacterial
- Hemolysin Proteins
- Hot Temperature
- Male
- Mutation
- Rabbits
- Vibrio parahaemolyticus
